Professor
M. Thomas Record
University of Wisconsin-Madison
Biochemist; Educator
Area
Biological Sciences
Specialty
Biochemistry, Biophysics, and Molecular Biology
Elected
2007
Research has developed thermodynamic and kinetic/mechanistic principles of protein-DNA interactions and assembly processes, especially the use of solute, salt and heat capacity effects to determine driving forces and driven conformational changes. Applications include characterization of large-scale conformational changes in transcription initiation by RNA polymerase, and in transcription factor binding in vitro and in vivo.
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