Dr.
Kenneth W. Kinzler
Johns Hopkins University School of Medicine
Area
Biological Sciences
Specialty
Medical Sciences
Elected
2019
Kinzler has made seminal contributions to cancer genetics helping to define many of the basic tenets of our current understanding of cancer. His team has helped define more than a dozen major cancer genes (e.g., APC, CTNNBI, PIK3CA, IDHI/2, ARIDlA, ATRX/DAXX and CIC), determine the pathophysiologic roles of genes in neoplasia (e.g., the APC/CTNNBl and TP53 pathways), developed novel genetic tools (e.g., transcriptome analysis, digital PCR) and pioneered the use of released tumor DNA (e.g. liquid biopsies) as a clinical biomarker for cancer.
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