George R. Stark

George Stark has addressed significant issues in protein chemistry, pathways of gene expression in eukaryotic cells and viruses, and the function of tumor suppressor genes and mechanisms of cellular response to extracellular signals. His development of the northern and western gel blotting techniques for RNAs and proteins power basic and applied science worldwide. Stark's studies of enzyme inhibitors led to the discovery of gene amplification in mammalian cells and the role of amplification in cancers. His investigation of genes induced by various interferons led to the discovery of transcriptional regulatory elements in cancers. His investigation of genes induced by various interferons led to the discovery of transcriptional regulatory elements that respond to interferon binding at specific cell surface receptors.