Frederick J. Sigworth

Frederick J. Sigworth is Professor of Cellular and Molecular Physiology and of Biomedical Engineering and of Molecular Biophysics and Biochemistry at Yale School of Medicine. Sigworth studied applied physics at Caltech and was a graduate student at Yale, working in the neuroscience laboratory of Charles F. Stevens. He received a PhD in physiology from Yale in 1979 and was a postdoc in the laboratory of Erwin Neher in Göttingen, Germany where he was a co-developer of patch-clamp techniques for single-channel electrophysiology. He returned to Yale as a faculty member at Yale in 1984. His current research is in the structural biology of ion-channel proteins, making use of novel cryo-EM methods.