Elizabeth C. Engle

Elizabeth Engle is a Professor of Neurology and Ophthalmology at Harvard Medical School, an Investigator of the Howard Hughes Medical Institute, and an Associate Member of the Broad Institute of MIT and Harvard. At Boston Children’s Hospital, she is a member of the Departments of Neurology, Ophthalmology and Medicine (Genetics), a member of the F.M. Kirby Neurobiology Center and the Program in Genomics, and a senior investigator for The Manton Center for Orphan Disease Research.

Her work has defined the human congenital cranial dysinnervation disorders and has been recognized by high-profile publications and by receipt of multiple honors, including the E. Mead Johnson Award for Research in Pediatrics from the Society for Pediatric Research, the Sidney Carter Award in Child Neurology from the American Academy of Neurology, a Research Award for Vision from the Alcon Institute, and election to the National Academy of Medicine. In addition to her research, Dr. Engle continues to care for patients, primarily consulting for children and adults with rare eye and facial movement disorders and other cranial nerve disorders. She teaches in both the clinical and laboratory settings, and has served on multiple committees that set the direction for neuroscience and ophthalmology research locally and nationally.

Engle received her B.A from Middlebury College and her M.D. from Johns Hopkins University School of Medicine. She trained in pediatrics at Johns Hopkins, in neuropathology at Massachusetts General Hospital, and in adult and child neurology in the Longwood Neurology Training Program and at Boston Children’s Hospital. Following her residencies, she was a research fellow with Louis Kunkel, Ph.D., and later Alan Beggs, Ph.D., in the Division of Genetics at Children’s prior to establishing her own research lab in 1997.