Amy C. Rosenzweig

Research focuses on the structure and function of metalloproteins on the molecular level. Recognized for work on particulate methane monooxygenase (pMMO), an integral membrane metalloenzyme that converts methane, the most inert hydrocarbon, to methanol. Studies determined the first and only crystal structures of this difficult enzyme and identified and characterized the dicopper active site. Also known for contributions to understanding metal homeostasis. Work revealed at a molecular level how intracellular metal ions are transferred between protein partners and contributed to the discovery of how metal ions are translocated across membranes. Advanced understanding of many additional bioinorganic systems through structural studies. Honors include the Royal Society of Chemistry Joseph Chatt Award (2014), the American Chemical Society Nobel Laureate Signature Award for Graduate Education (2006), an Honorary Doctor of Science Degree from Amherst College (2005), a MacArthur Foundation Fellowship (2003), and a David and Lucile Packard Fellowship (1999).